puntificate Share definition Flag 1. To make puns for the delight and/or irritation of friends and family. 2. To make puns in excess. Jacob would groan and claim to hate it when Ed would puntificate, but in reality he just envied Ed's acumen for wordplay. puntificate by Teddallo March 25, 2008 0 0 Get merch Get the puntificate mug. Buy Now — $32.95 See more merch