An exclamation when an upcoming event or deadline is approaching that will most likely lead to hardship. This can be used synonymously with the phrase "Your gonna get raped".
Dakota - "Man, I have two test, a paper, and finals are coming up... I am going to fail out of college...."

Travis - "Well damn, you better prepare your asshole.."
by xSSKT April 27, 2011
Get the Prepare your asshole mug.