1. Toothless, inbred zombies wandering South Florida in search of "pain clinics", where oxycodone prescriptions are handed out like Halloween candy. Known pillbilly states consist of: Kentucky, Tennessee, Ohio and West Virginia.
Look, there's another truck load of pillbillys from Kentucky pulling into the pain clinic parking lot.
by thebasher November 09, 2009
3 more definitions
Someone strung out on prescription pills.
Jennifer Sires is a pillbilly.
by Scott October 08, 2003
some from appalachia area hooked on narcotics including oxycotin
just about everyone in eastern kentucky can be called pillbilly
by starkeyscott May 28, 2009
A person from West Virginia,Ohio,or Kentucky that travels down to Broward County,Florida to buy prescription drugs and take them home to abuse them and/or sell for profits. Or just a hillbilly with a Oxycontin/30mg pill addiction.
I know this guy that told me,Kentucky has the most prescription drug abusers. He was a total "pillbilly"
by Big Crutch July 12, 2011