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1.
An extreme state of confusion, insanity, fear.
Johns mom went perplexic when he vomited all over the carpet.
by Mung August 17, 2003
 
2.
When a dyslexic person is perplexed. Usually due to the fact that they are dyslexic.
All these letters and numbers got me perplexic!
by Twerkxqueen23 July 14, 2014