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1.
A state of retardedness where the subject is under such delusions that an action like wearing their pants on their own head seems like a rational thing to do.
Medical Chief: What can you tell me about the patient?

Psychologist#1: When brought in he was in a hysterical state. At the time there was no way of contacting him. We've had some limited interaction with him once he calmed down.

Medical Chief: Could you elaborate?

Psychologist#1: Well, so far, he has insisted on eating soup with a fork, wasn't able to grasp that an on/off button only has two modes and shows equal amount of amusement from contemporary music as well as advertising jingles.

Psychologist#2: The subject seems unaware of his surroundings, shows poor to none skills in human communications and lack concept of the basic laws of physics.

Medical Chief: So pretty much pants on head retarded?

Psychologist#1: That would be the medical term, yes.
by IamKenny April 14, 2010
 
2.
Some one so stupid you can just see them waring thier pants on thier head and making loud unintelligable noises and drooling.
Tard: * removes pants *
Me: WTF
Tard *places on head*
Me: God fucking damnit not another...
Tard: flarf narf *drool* can i has hug? *SHITS SELF*
Person2: fucking text book pants on head retarded situation.
by TheStorey November 26, 2007
 
3.
Someone to be so retarded that they wear their pants on their head instead of on their lower body region.
Timmy is so pantsonheadretarded
by Domgod July 14, 2008