P.O.L.O. 

Players Only Live Once

P.O.L.O. by Travis June 10, 2003

P.O.L.O

Please Only Live Once

YOLO
P.O.L.O <.<

P.O.L.O by Spankyou September 12, 2012

P.O.L.O. 

Means;Pants Off Legs Open

Woman on phone; "I'm P.O.L.O., are you coming over?"

P.O.L.O. by toymi69 May 17, 2008

P.O.L.I.T.I.C.S 

an Acronym to remember who's really speaking for you.

Preaching
Opinions
Lacking
Intelligence &
Tact
In

Controversial
Shit

Dude 1: Hey man , I can't decide which politician to vote for!
Dude 2: Do your research and use the acronym P.O.L.I.T.I.C.S
*a few hours later*
Dude 1: Bro You're totally right!

P.O.L.I.T.I.C.S by riddlecker January 16, 2018

P.O.L.O

P.O.L.O. May be used in reference to what you would like to do to girls at parties without appearing to be a perverted nymphomaniac. It stands for:-
Panties
Off
Legs
Open

Wow I saw this P.O.L.O today. New model, Red with all the bells and whistles.
Actual Meaning: I saw this girl I'd like to f#ck, pretty young with red hair and soooooo fine.

P.O.L.O by Tenchu_X March 17, 2011

P.O.L.O. 

Pussy On Level One

Come get some

P.O.L.O. by Darius Valentine July 8, 2003

P.O.L.O

Playas Only Live Once

It true P.o.l.o

P.O.L.O by KingTTW2 April 16, 2010