p.i.m.p.l.e Share definition Flag acronym, Pissing (or piss) in my pants laughing ecstatically. Em: that joke was so funny it made me p.i.m.p.l.e! p.i.m.p.l.e by *Emshaw March 11, 2009 0 0 Get merch Get the p.i.m.p.l.e mug. Buy Now — $32.95 See more merch