Top definition
omfgstfu stands for: Oh my f*cking god, shut the f*ck up.

Used when you are really angry at someone and just wish they would shut up.
Girl 1: So like, she's like suuuch a bitch like wtf. She's soo not cool and stuff.
Girl 2: omfgstfu. she's my friend.
by athy16athena February 08, 2009
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