a response to anything suprising, frustrating, or lame. The origin comes from the Sarah Silverman show in which she decided to make a cool word.
Person 1: You like my new haircut?
Person 2: OHZAY!
Person 1: *gasp* fuck you too.
by sweetshit December 12, 2008
Oh Zay is a word used to describe things in a negative way. It's like saying 'thats retarted!'
"Oh man that is sooo oh zay!"
by nobody use this name January 13, 2009

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