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Any grenade launcher, be it an M203 or a GP-30, used on a video game. Specifically online on Call of Duty: Modern Warfare or Modern Warfare 2. It requires almost little or no skill to effectively get kills with it. Just aim in a general direction of wherever you think the enemy might be, and it'll get the job done without giving your enemy time to avoid it or retaliate.

Surprisingly, despite its name, it's not primarily used by noobs, or newcomers to the game. It's actually used more by assholes that are well into the game already but only use it to piss off their opposing team. And unfortunately, they usually do succeed in pissing off their enemy which could (and normally does) result in the enemy team changing their class to a noob tubing class while saying something like "Oh you wanna noob tube bitch? I can do it too", and that results in an entire game session being nothing but noob tubes and/or RPG's, depending on who's in the game.

Highly disliked by the majority of the gaming community. Avoid noob tubing at all costs to ensure that you don't start a tubing chain-reaction.
Teammate 1- DUDE!! This guy is using his fucking noob tube again!

Teammate 2- I swear to god. If i get tubed one more time i'm gonna bust a nut.

T1- Alright fuck this game....

T2- Come on. Don't rage quit.

T1- *disconnects*

T2- Son of a bitch *facepalm*

Noob Tubed 

Particularly used in the Video Game 'Call of Duty: Modern Warfare 2'. Where a player uses the Grenade Launcher attachment for their weapon to kill just 1 enemy player, rather than a group of enemies.
Player 1: I just got noob tubed!
Player 2: I hate people who noob tube...
Noob Tubed by SquashedBanana October 26, 2010
The M203 rifle mounted grenade launcher used by newcomers to the videogame Call of Duty 4: Modern Warfare, specifically its online multiplayer. while requiring no skill or effort, this weapon also barely hurts the user while completely obliterating any who get in its path. This is seen as a cheap weapon only acceptable for use by the worst of players at this particular game.
"Wow he is like a level fifty five and he still uses that cheap-ass noob tube!"

Noob tuber 

a n00b on CoD 4 who only uses the grenade tube to kill you.
John: I just got tubed
Frank: boot the little noob tuber then
Noob tuber by camazonDamazon April 14, 2008
A gaming term for an under-mounted grenade launcher such as the M203 or any other kind of launched explosive (RPG, Thumper, etc) used in first person shooter games such as Call of Duty: Modern Warfare 2 or Battlefield: Bad Company 2. Use of such a weapon to get kills is considered 'cheap', since it requires very little skill to use. 'Noob' is a term for a newcomer to a game, and is used as an insult in gaming communities.
Damn, that noob got me with his noob tube for the eighth time this round!
Noob Tube by ecyrblim April 10, 2010

Noob Tuber 

A really annoying person that keeps killing u with a grenade launcher in Call of Duty
That noob tuber is making me want to throw my controller through my tv
Noob Tuber by Dr.Crunch December 11, 2009