A chronic painful condition that effects the muscles or joints in the hand, fingers and/or forearm after playing videogames too much.
Dude, I played Final Fantasy for three days straight, but my Nintendonitis flared up so I couldn't play anymore.
by Aeronius January 16, 2006
1 more definition
The cramp you get in your hand from playing video games, especially between the thumb and forefinger.
I was winning blades of steel until my old Nintendonitis injury took me out.
by hkmtbr December 06, 2008