Running away from a violent confrontation, particularly using Nike sports shoes or where another person may resort to using a small arsenal to shoot his or her way out of it.
We was running low on ammo, so we used the Nike defense and hauled ass outa there
by Lior Bar-On July 13, 2004
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A defense used on occasion in a court of law. Based on the assumption that if someone is wearing Nikes, they run at abnormally fast speeds, thus allowing them to indeed appear to be in two places at once.
State Attorney: You expect us to believe this alabi of being home at that hour when our records show you had just arrived in Dallas?

Defense Attorney: Nike defense! Nike defense! My client was wearing Nikes Your Honor.
by Super Gerbil July 15, 2004
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The surface to air missile defense system the US used from 1955-1974. Nike surface to air missile system was named after the winged goddess of victory in Greek mythology. Two versions of this system defended the U.S. and other places from hostile aircraft, the Nike Ajax, and the Nike Hercules. Their primary purpose was to destroy any Soviet strategic/supersonic/longrange bombers like the Tu-95 Bear, or the Tu-160 Blackjack, or Tu-22M Backfire that ever came into US territory. There was never a need to use these nuclear tipped missiles, thank God.
There were 16 Nike Defense installations in the Detroit area.
by Spartans! December 3, 2004
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