"It's phony, goddamn it but mysto and after a while it starts to infect you, like an itch, the roseola." p.19 of The Electric Kool-Aid Acid Test, by Tom Wolfe.
by ASlateReader August 20, 2011
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A friend who has fallen out of communication with his/her crew.
Ted has gone mysto on us ever since he started coaching his kids. Hope he pops up for a beer some day.
by selgreco March 30, 2018
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It was mysto why there wasn't a definition on Urban Dictionary for "mysto," so I made one, immediately after some dumbass on Slate said there wasn't one, rather than just making one himself.
by Kenboy August 19, 2011
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An abbreviation for 'mystical'. Coined back in the sixties when any experience with drugs were considered mystical.
Matt: "Yo dude, did you try some of that trippy acid?"
Pete: "Yeah man, it was mysto, dig?"
by Kidnap The DJ August 18, 2011
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An unsolvable mystery. A man appearing to be a woman or vice versa.
That fella is a real mysto, oh wait, it's not a fella at all.
by Bill from RNOC August 19, 2011
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Mysto is an anime tiktoker his favorite anime is dbz he never misses and he usually comments W or L on posts he sees.
by Flip900 March 18, 2021
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