Top definition
The act of two females (preferably lipstick lesbians) engaging in each other's bodies in a sort of a locking fashion by connecting one's mouth to the other's snatch and vice versa.
Dude 1: I was surfing some online porn the other day and came across a mean muff-lock.

Dude 2: Nice! Were they hot?

Dude 1: Of course, any chic playing in the box is hot!
by Beauhemian October 20, 2006
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