Top Definition
To agree.

person #1: I believe in a thing called love.

person #2: I mosco.
by BarryObamie December 03, 2008
1 more definition
Used to call someone a nuisance, someone that bugs allot. Mosco in spanish literally means "Mosquito", a very annoying bug that constantly follows you where ever you go, well thats what a Mosco does...he/she will tag along and bug when and where theyre not wanted.
"hey Freddie, lets leave through the back door, I dont want that Mosco George to see us leave" Freddie replies: "Aww man youre right, tell that Mosco I aint got room in my car"
by El Gallo NEgro October 08, 2007

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