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1. Any female who is extremely bitchy.
2. A total cuntress.
3. A woman of unmatched anger or resentment, most often during menstruation.
My boss wouldn't let me have the day off because she's a total megacunt.
by Jim Sammartino May 22, 2008
the dirtiest of all bitches the nastiest of the nasty. the end all of cuntdom
matt: most girls named ashley are cunts.
joe: true but craig is a megacunt.
matt: this is true.
by juggles411 June 05, 2011