Top Definition
A term first coined by Dr Gregory House in season 6 episode 13 to denote the feigning of a practical joke on oneself to avert suspicion from other people about one's guilt as a prankster.
Wilson:You created empirical proof that I didn't prank you selling me on the notion that you didn't prank. Maybe you self-pranked.

House: I don't masturprank
by The Gonzo Lecture March 25, 2010

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