Top Definition
Dirtiest, Nastiest, and Most disgusting shit you will ever take in your entire life. A shit that when you are done, you will vomit, then the smell will linger like a skunk's until you bath in tomato juice.
Dude, I remember when i had a Lupro in the 4th Grade and no one would hang out with me until Junior year!
#diarrhea #shit #nick #gnarly #sickening
by Boo Motherfucker April 01, 2006
5 Words related to lupro
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