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1.
a super sexy beast who supersexybeastness is too much for any guy to handle.

in other words, they don't know what to do around her so they become unintelligible with their words.

OMG, look at her, she's totally a Lois, YO!
by kdsjfklsdjir January 09, 2008
 
2.
LOI
acronym for laughing on the inside
When she heard her betrothed would wed another, she was crying on the outside, but LOI.
by elsquid June 30, 2013
 
3.
LOI
An acronym for "laughing on inside" or "laughing on the inside".

Created to replace "LOL" since most people do not actually laugh out loud when they type it in a message.
Girl #1: "So I totally had sex with Rod the other day"
Girl #2: "LOI! You're such a slut."
by SchnauzerDouser December 07, 2006
 
4.
A unique kind of person, he/she is a nice, charming and funny person, always helping out and caring for others. They give the best hugs and can get quite jealous over the person they love. They will not stop chasing the person they like and are quite romantic.
I hell want to marry a lois, theyre faithful and give the best hugs

Lois is such a sweet girl, i love her to bits
by Altanonymous November 20, 2012
 
5.
A Lois is an AMAZING, friend who is always there for you. A Lois is the best friend you could ever wish for! She is a nice, caring, funny and loyal friend who will never let you down!
1: Who's that?
2: Must be a lois
by Clutts xx October 10, 2011
 
6.
A Hilariously funny Girl, with a great sense of Humor, Beautiful, Amazing eyes, and an Irresistable power No boycan refuse. Will make a great Comedian in Life.
Wow Lois, You are so funny.... marry me? loool :)
by Mr.Redunkulus December 07, 2010
 
7.
A big boobed hot girl that all guys want to do.
"Did you see that hot mumma over there?"
"Oh i can tell you mean Lois without even turning around"
by Lac99 February 13, 2009