It means to speed over potholes.

It comes from a joke in my city about this one road that has a lot of potholes and a high speed limit. But the road is ironically the main way to get to the hospital called Holy Family. Highway to Holy Family has claimed many lives.
Officer: okay so who is responsible for this accident?

Person: Not me, that other asshole was driving like Holy Family.
by Sacredfart June 19, 2023
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