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1.
See as a friend; meanings are synonymous.
She said that I gave her sort of a "family" vibe, and I knew that that translated to "you're like a brother to me."
by Zalis March 29, 2005
 
2.
One of the worst possible things a girl can say to you. you have liked her for a long time and have thought that can now get with her, then she drops the bomb that your like a brother to her. the shit may then proceed to hit the fan.
"Sally how about having sex"
"You know i cant do that with you, you're like a brother"
by RekabmaS February 04, 2009