Top Definition
a racial derogatory term for an African American which is referring the person to a primate because of the similar body features (head shape, nasal passages, shade of skin, etc.)
"That fucking knuckle-runner, Dwane Garrett catches e every god damn ball."
"I know fool, send that nig back to the jungle."
by Joe T Real January 26, 2008
5 Words related to knuckle-runner

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