1) Response to when someone says something overtly sexual.

2) It's a school night maybe she will keep it in her pants for once.

It's unisex. Ironic if said to a girl so completely fine.
similar to: "relax buddy, no need to get riled up there."
or
Person A- "DAYUM...the things I would do to that ass."

Person B- "Buddy, keep it in your pants."
by Prophite May 2, 2008
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Person One: Bro, I ordered my cheese like 45 minutes ago, where the hell is it?!?
Person Two: Dude, keep your pants on, its coming.

Person One: What in the world made you think I would take my pants off?
Person Two: I don't know, in any case, your cheese will be here soon.

Person One: Nah man, this ain't right, I'm calling the manager ... And taking my pants off!
by welcometoforever March 9, 2015
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What to say to someone when they're getting too excited about something (can be anything).

Another way of saying "Calm down!".
A: (Person getting too excited about something)

B: Ok man, keep your pants on!
by El_Barto October 21, 2004
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1. (male) To refrain from engaging in intercourse

2. (both sexes) To mind one's own business, keep out of other people's personal lives and affairs.
1. Hey, it's best to keep your dick in your pants right now, since you didn't bring a condom. You don't want to get an STD, do you?

2. A: Hey, what's wrong? You look upset.

B: Keep your dick in your pants. I don't have to tell you anything.
by MadameTesla July 28, 2015
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Refrain from having sex; avoid getting seduced by or wooing attractive women for sex.
Joe, chasing dem ho's is going to ruin your college career. Keep your pecker in your pants, boy!
by shrao October 2, 2022
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