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1. Fan Interference
A baseball metaphor where a so-called friend cock blocks you.
I was macking with that chick and then Bobby totally came over and committed fan interference. What an asshole!
2. run interference
To deflect attention away from someone else.
My buddy and I used to run interference for each other by taking turns playing racquetball with the husband to get him out of the house, so the other one could visit his home to fuck his wife.
3. Running Interference
Entertaining the obligatory fat chick in every group of hot chicks so your boys can get a piece off her friends.
I ran interference last weekend and my bed still doesn't smell right.
by AspiringdeitY Aug 5, 2003 add a video
4. to run interference
helping a friend get laid by entertaining her annoying friend, at any cost
Ryan was trying to get into beautiful Tiffany's pants, but her fat and annoying best friend was cock-blocking him, so I ran interference on the bitch.
by David Stewart Nov 10, 2003 add a video
5. run interference
to protect someone esle from the attention or criticism due for a particular activity; To help someone in the performance of a task, but not directly assisting in the task.

From American Football where certain players are detailed to prevent the opposing team from tackling the palyer with the ball, by interfering with them.
a:"How am I gonna get these Playboys into the house while mom's there?"
b:"You go round the kitchen door, I'll run interference by showing her the job I did on the lawn"
by D F Stuckey May 12, 2004 add a video
6. run interference
originating from football, to attract attention to yourself or throw yourself into harm's way to help out a friend.
your ex just got here - you leave out the back and i'll run interference.
by Erin May 13, 2004 add a video
7. run interference
To cause a commotion make a spectacle of one's self or to just generally draw attention to yourself in order to allow someone to do something.
I had my sister run interference with my boyfriend while I got this guy's number
by Chelizsa Jun 1, 2004 add a video
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