When someone is rather unattractive before a weight loss, face altercation ( example, nose job, jaw realigning,etc...) was not full of themselves before the transformation, but after becoming so called "hot" or attractive and becomes a major bitch and having major changes in personality, etc.. super judgemental to other.
"Heidi totally got a case of "Ugly-Hot Girl Syndrome" when she got her face done. She is a total bitch now and completely full of herself."
by Trex2344 May 8, 2010
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When a girl that used to be hot ages poorly or gets fat but still acts like a princess hot girl
Jess must have FHGS (former hot girl syndrome) if she thinks someone is going to buy her a drink dressed like that.
by Airik May 5, 2016
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When a girl suffers from attraction to a hot guy, usually one of her best friends or someone that she knows it would be a huge mistake to get involved with, and won't allow herself to go out with/make out with them, but can't stay away either. She will continue to toggle back and forth between wanting to jump his bones and wanting him to die a horrible death.
Girl1: Oh, my god those two BOTH make me have Hot guy dilemma syndrome!

Girl2: Bummer girl, you should just hurry up and date them so you can move on to the just hating their guts phase!
by SufferingNsocorro March 31, 2009
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When a girl who is told or given the impression that she is more attractive than she actually is and thinks that she owns the word and acts like she is above the average person; a mix between a pick me and a cunt
Girl: Gtfo of my face you freak
Guy: She’s a 6 at best but thinks she’s a 9 because of all those thirsty fucks sucking at her toes, classic case of hot girl syndrome
by Someone smarter than you December 5, 2021
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N; The withdrawal after seeing a hot boy (usually while traveling) and knowing you will almost definitely never see him again
Omg that guy at the rest stop is totally going to give me Hot Boy Syndrome...
by Bitty bae November 11, 2019
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When you or your pet has so many medical problems there's no single diagnosis for all of them
What did the veterinarian say is wrong with your dog?

They said she's got so many problems it considered hot mess syndrome!!

jacked up messed up bad
by Tragus February 7, 2017
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