Adv. Used to define something really, really negative, usually in a promiscuous way.
That girl is herpa nasty, she made out with four guys at the party last week.
by musicsuburb October 9, 2006
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Herpes you receive from stupid unprotected sex with a stranger, usually under the influence of one or more drugs including but not limited to alcohol, ecstasy, or dissociatives
Yeah I had a one-night stand with this chick and ended up getting herpa derpes
by rawkies July 12, 2010
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When a employee of McDonald's who has contracted Herpies pisses in the McFlurry machine before making the McFlurry.
Sarah: You know that douch that always came through drivethrough?

James: Yeah.

Sarah: Today I gave him a good taste of my special Herpa McFlurry.
by DatNucka January 18, 2011
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A serious case of STS: Sexually Transmitted Stupid.
I heard Mary got drunk and had sex with her ex-boyfriend last night!" "Yeah, she has a bad case of herpa-derpies.
by funthatburns February 14, 2011
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Visible, oral Herpes on a hood rat (hoodrat can be either female or male, as long as the person has participated in hoodrat like activities).
"That bitch Liz got the herpa derp from daniel."
by El Libertine March 22, 2010
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A combonation of ghanareia, herpes, and syphilis....i did not spell none of that right!
She has gona-herpa-syphilades!
by Chad Chad Chad December 6, 2006
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