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1.
To miss a close shot.
To take something that should be taken for granted and mess it up.
Used mainly in sports or competition.

That guy just had a wide open layup and he pulled a guzek!
by Blackdisk September 05, 2008
 
2.
Someone who refuses to use a turn signal in any and every conceivable situation for no apparent reason. Often talking on the phone or texting.
That guzek just cut me off!!!
by chitownfan0510 March 23, 2009