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Gone to rat shit 

This expression was in common use in the British Royal Navy, certainly in the eighteenth century, but is probably even earlier than this. As these ships were built of wood and powered by sail, emphasis was given to fire power and hull design and as a result crew accommodation and food storage were extremely primitive. This meant that foodstuffs were subject to attack and contamination by the numerous rats living on them. When this happened, the food or other stores, such as sails or ropes that had been destroyed by rats or so contaminated by them as to be totally unusable, would be described as having 'gone to rat shit'.
The expression became more widespread due to its use within the Royal Dockyards and still later within civilian establishments. Its meaning also began to change and expand so that it came to mean anything that had become broken, damaged or useless for any reason not just rat attack. It also began to be applied to people where it meant someone who had changed from being pleasant and personable to unpleasant and disagreeable. It is also applied to someone whose health is failing, affecting their appearance.
Some Americans believe that since Donald Trump’s election everything has gone to rat shit.
Gone to rat shit by AKACroatalin February 24, 2017
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Gone to rat shit 

This expression originated with the British Royal Navy from the time of the wooden sailing ships. Storage of food aboard these vessels was quite primitive and foodstuffs were subject to attack by the numerous rats living on them. Frequently food, or other stores, would be destroyed by rats or so contaminated by them as to be totally unusable, the crew would then say that whatever had been destroyed had 'gone to rat shit'.

The expression became common in the Royal Dockyards where its use expanded to mean anything that had become broken or unusable whatever the cause. The use of the expression further expanded to mean someone who had changed from being a pleasant person to an unpleasant, grouchy bastard, or someone whose health was beginning to fail.
Malcolm's made another major fuck-up with the website, it's all gone to rat shit.
Yeah, when Sally told him about it, he screamed at her like it was her fault! He never was very nice, but now he's really gone to rat shit.
Malcolm's gone to see his doctor again, he really has gone to rat shit.
Gone to rat shit by Croatalin December 20, 2013

gone to ground 

To take evasive action in order to avoid further attention. To "lay low."
Ever since we exposed the Mayor's sleazy secret policy, they've gone to ground on this issue.
gone to ground by Timothy Harris January 5, 2009

gone-to-shit 

When everything has fallen to bits, totally buggered, fucked beyond recovery, finished.
"This job has gone-to-shit"
gone-to-shit by zyncwarrior November 2, 2013

gone to shirt 

When something has got so bad it's affecting your typing.
This place has recently gone to shirt.
gone to shirt by Uncle Whippity February 17, 2005

gone to plaid 

When something moves entirely too fast (reference from Spaceballs) especially in the case of a relationship.

Joe - Hey did you hear Ken and Sue are engaged already?
Mike - But they just met last week!
Joe - I know, they've totally gone to plaid.
gone to plaid by conipto2 November 10, 2006

gone to pot 

An item which is broken, defective or substandard. Two explainations have been historically applied. The first is that in olden times when food was scarce, people would leave the bones, fat and undesireable portions behind after eating their meal. These second-rate items would be used for soup the next day, so as such, the poor-quality leftovers would "go to pot". The second (and more plausible) explaination is that in the days of the industrial revolution and early mass-production, assembly workers would occasionally find a defective or out-of-tolerance part which was not suitable for use. This part would be sent back to the smelting room to be melted down and re-cast a second time. Since the smelting was done in a giant pot, these defective parts had "gone to pot". In either case, the phrase gained popular use by the American homeowner who would occasionally wear out an item which would fail- often at an inconvenient time.
Frank didn't want to take his car in for routine maintenance. I wasn't surprised when his vacation was ruined after the car went to pot last summer.
gone to pot by Frank Klaune May 13, 2005