A request for praise which can be issued either by the recieving party or a third party.
Give it up for my man DJ Mike!
by Spirit Bear February 28, 2004
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the act of a female giving someone sex.
dont waste your time or money on that bartender the only one shes giving it up to is her boyfriend the bouncer.
by tellitizaman September 15, 2010
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To cease efforts now otherwise pointless
"Just give it up man, she's not interested in you."

"You'd better give it up, unless you're rollin' for a bitch-slap."
by Krispy February 29, 2004
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You're not getting your money till you give it up.
by Anonymous June 17, 2002
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A catch phrase from the fictional TV show "Galaxy Quest" in the movie Galaxy Quest (1999). Became a ongoing joke for foregoing logic and forging ahead with little plan
Inmate 1: "Why do you insist on trying to escape from the cell with a toothbrush. You will never be able to get through the walls with that."
Inmate 2: "What else are we going to do. Never give up Never Surrender"
by Epic Borris September 13, 2013
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phrase for "allow to have sex with", as if some girl's skanky cooter is like a wonderful gift that only a few very special dumb ugly men will have access to. Usually used by young girls who think their "body is a temple", or some stupid shit like that, and generally only use sex as a bargaining chip to further manipulate any man near them. A phrase usually used by the most conniving, manipulative, man-hating bitches on the planet - i.e. most of them.
"I'm not going to give it up until you buy me dinner, a new rolex, a sports car, and a mansion asshole! Get used to it 'cuz this is as good as it gets you piece of scum! I rule the planet because I have a vagina!"
by muntumbo mo klick January 5, 2007
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