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To Have Sex With Someone.
Jack: None Of Those Girls Will Get Off With You
Simon: Arrh Mayn!
by x- Saucy Kisses -x June 14, 2007
to be really excited about something
I get off on Seinfeld
by Bungalow Bill November 07, 2001
To French kiss.
I got off with Bob last night.
by Emerlee October 12, 2003