1. to have an orgasm

2. to copulate

3. to masturbate
He is in his room getting it off.
by Light Joker August 23, 2005
Sexual excitement
What a wonderful planet we live on where we can get it off and get it on at the same time.
by B laBelle October 01, 2009
Yet another lolcat caption meaning get-it-off used In "I CAN HAS CHEEZBURGER?" By a black cat with atoy mouse.
Cat: HOLY CRAP MOWSE GETITOFF GETITOFF
by lolcat SUPERFAN!!!111!! January 22, 2010

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