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A combination of the two words "Gay" and "Anime", it could mean one of two things.

1) Hentai that includes at least a 75% majority of the same gender as you.

2) For people who just highly approve of Anime in general, they will tend to call it Gaynime.
1) Bob: "Hey, go to this site."

Jack: "Uh, okay.. OH MY GOD, THIS IS GAYNIME! You sicko!"

2) Sam: "Two more days till Didji' comes out!"

Jill: "FF is way better than didji!"

Mark: "Stop fighting over your Gaynime!"
Gaynime by Batman oCourse March 17, 2010
Related Words
A gay man with a grenade up his ass
Tha guy has been gaynad(ing.)
GAYNADE by daftlad_uk April 11, 2003

gaynamie 

Anime that contains gay or lesbian characters in their anime story. Combination of both Yaoi or Yuri types of anime series shows.
Kristi and Jacqueline are both girls who loves to watch gaynamie late a night.
gaynamie by Vuong January 19, 2008
When your homosexual sibling takes you and locks you in their room, and tries to make you gay.
I'm gay because my brother gave me a gaynade.
gaynade by CamMartians August 28, 2015
When you want to Nae Nae but you're gay

The name of a certain Podium in Auschwitz
"Ah damn, I can't Nae Nae.... I'll just Gaynae"

"Millions Killed by the orders from the Gaynae"
Gaynae by Memecide March 1, 2021
This references anyone named ethan because anyone with the name Ethan has an underlying homosexuality that they fear people will judge them for even though people already believe that they are gay
“I know a guy named ethan and your right that is a pretty Gay name”