1.) Used to denote a direction that is highly unfortunate for the the traveler.

2.) The direction of downtown Detroit from wherever you are.

3.) Adverb: Just generally bad.
1.) Guy: "He just stole your car!", Fucked person: "Which way did he go?", "Fuckwise!"

2.) Guy in Ann Arbor: "Dude, which way's Detroit?", Other guy: *points east* "Fuckwise"

3.) After a hard exam: "That exam fucked me fuckwise!"
by jlarg October 22, 2009
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Adjective used to denote an object, device, or system which has inexplicably gone horribly wrong.
John: dude can you give a lift this morning?
Anna: nah my truck’s gone fuckwise and I’ve not had time to fix it, I’m taking the bus today
by fickityfack September 14, 2020
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