Basically, means to just for the person to stop everything he/she is doing and find the nearest gun, point it under their chin and pull the trigger. That way they will no longer bother you and you can get some peace and quiet without their pure bullshit spewing from their mouths. If one continues you to harass you after you say this, you legally have the right to make them discover what your fist tastes like. They cannot sue you for any reason.
Latin origins of GO Fuck yourself:goeth fucketh yourselfus
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Go have sex with yourself.
Guy 1: Hey bro wanna fuck?
Guy 2: Go fuck yourself
Guy 1: ok *takes dick and puts in asshole.*
by dabigmothafucka July 15, 2023
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To tell someone to go away or to just leave you alone or never talk to them ever again.
PJ: Hey can i eat dinner at your house ?
AJ: yeah right, go fuck yourself.

ahhaha

COMEBACK: if your a male or female and an ugly opposite person of sex tells you to "go fuck yourself", you should reply :"I'd rather be fucking myself then fucking you". ahhaha
by jUiCY JAYDA September 18, 2007
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almost same meaning as go to hell, but in a much more rude way
boy: Hey babe, care to come with me??
girl: go and fuck yourself
by number1dubagoor July 30, 2015
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A command for someone to get lost (especially from the person that says it), usually as a result of extreme annoyance. Literally it means for them to masturbate themselves, so they aren't inclined to harrass and receive sexual pleasure from the person they are annoying. It's more stinging than "fuck off" because it implies that they could not or should not find anyone else to have sex with, so they need to use the self-manipulation.
"lol, looks like i beat you at WoW again..." "go fuck yourself"
by Mr. Zed September 11, 2006
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The type of insult you would use on someone who's wasted over 1000 hours of their life playing Counter-Strike: Global Offensive
"Man, you should just CS:GO Fuck Yourself, you lousy no-life"
by Obsidian_Linguist April 19, 2017
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A more forceful equivalent to get lost or go away. Many variations exist, including hide-and-go-fuck-yourself. Expression by a first party for a second party to leave the vicinity or simply stop associating with or annoying the first party.
He wouldn't leave me alone, so I told him to go fuck himself.
by NeNay June 2, 2005
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