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1.
A .45 caliber handgun or pistol, usualy used in urban slang such as rap.
Common to words such as tre deuce being a .32, deuce deuce being a .22.
"Looked up and I seen Swift shootin it out
But I can't see who he's shootin it out with
But Denaun's right behind him squeezin his four fifth"

-Eminem (one shot 2 shot)
by chris November 15, 2004
 
2.
a .45 handgun

must write 20 letters
must write 20 letters
must write 20 letters
i keep my four fifth tucked in my button up
by thebay707yeeyeeyee! February 25, 2006
 
3.
a .45 pistol.
i capped yo ass with a four fifth.
by Anonymous October 05, 2003
 
4.
another word used in place of saying forty five, a colt 45 gun.
man i got in the club with the four fifths, let some shit pop off iam ready.
by bert2 June 29, 2005
 
5.
noun, slang.

an urban or slang term used to describe a .45 caliber pistol.

origin: southeastern Virginia (Virginia Beach/Norfolk), Newport News
"hit 'em with the neener man/
or that four-fifth guaranteed to lean ya, man, whoa" - Malice of the Clipse, on Baby's "What Happened To That Boy"
by C_Smith April 30, 2006