look up any word, like dirty sanchez:
 
3.
"Five Loko: When Four Just Isn't Enough"

Adding any sort of hard liquor to a Four Loko, preferably whiskey. A practice most commonly seen amongst broke college students, and anyone else who is either A) adventurous or B) has a death wish. Typically results in a crazed, bear-like, drunken state.
Man, this Four Loko just isn't doing it for me. Whip out the vodka and let's get some Five Loko going.
by sevflorenz November 14, 2010
 
1.
Mixing the new (caffeine-free) four loko with a 5 hour energy to regain its former glory...

They changed the formula and we're changing it back.
We're going five loko tonight!
by drunk@jhu January 23, 2011
 
2.
When one mixes Four Loco malt beverage with vodka it is a Five Loco.
Damn that bitch be twerking on that Five Loko tonight.
by matt derpson October 08, 2013