Top Definition
The state of having screwed yourself in the ass.
I was enjoying regular bowel movements, but then I started fillling up with carrots instead of eating bran cupcakes in the morning, and it was a real case of exacerbation.

Why can't Priscilla sit down?
He's all exacerbated.
by skeptical hippo July 17, 2010
To annoy
The other day you exacerbated me soooo bad.
by Chasumitity August 28, 2003

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