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Ed Zachary Disease 

Ed Zachary Disease is when your face looks exactly like your ass, meaning you are extremely ugly.
"Ed Zachary Disease is when your face rook Ed Zachary rike your ass." - Dr. Chang of China
Ed Zachary Disease by -Brad- May 24, 2006

Ed Zachary Disease 

When someone's face looks Ed Zachary like their ass.
Once, an ugly girl that was making a pass at me described that she wasn't feeling very well.
I said, "Well, if I were a doctor, I think I might diagnose you with Ed Zachary Disease."
She asked what it was and I said, "When your face look Ed Zachary like yo ass."
She wasn't amused.
Ed Zachary Disease by Roy L'Ourtiere September 7, 2008

Ed Zachary Disease 

When a person's breath is SO BAD that their mouth smells "Ed Zachary" like their asshole.
If you do not brush your teeth you are going to have Ed Zachary Disease, and no babe will want to kiss you.

Ed Zachery Disease 

Very nasty disease that prevents women from getting dates or having sex. This was coined by Dr. Kayoto, the very well-known Japanese sex therapist.
Your probrem vewy bad, you haf Ed Zachery Disease."
Ed Zachery Disease? What's that?"
"Vewy sad. It's when your face rook Ed Zachery rike your ass."

Also see Butterface, or ButHerFace
Ed Zachery Disease by TimmyH September 8, 2006

exzachary 

A hybrid between exactly and Zachary. A step above absolutely positively completely and utterly blended with the name of the most upbeat kid in town. Exzachary has more meaning than can ever be defined.
Chelsea: That's exzachary what i was going for!
Rachel: I know exzachary what you mean..
exzachary by chelly:) May 25, 2011

exzachary disease 

When someones face looks exzachary(excactly) like their ass.
George has pretty severe exzachary disease
exzachary disease by Betabox March 31, 2008