43
Short for Down-syndrome. The term is commonly used to label bronies, or also known has the mentally ill people who watch the show My Little Pony or to what they refer to as, MLP. The term is also commonly used on really stupid people on the internet that try to troll.
Anti Brony: Ewww look a brony! Stay away he has downs.
Normal Person: Now that I think of it...bronies do have downs! Ahhhhh! Run!
by Trjx March 30, 2014
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44
"down" can refer to the desire to get high (usually on marijuana)
by Zippyz February 04, 2008
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45
Short for downs-syndrome. It is commonly confused with down-syndrome, but each is completely different.

Downs-syndrome is where you hate everything.
"Have you ever been to www.downs-syndrome.tk"?
"No, but I'm sure he hates everything."
by Downs March 20, 2004
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46
(v) To bash someone so hard they fall over.
I'm gonna down ya!
by Rohan November 16, 2003
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47
Someone who is repetatively stupid or dumb!
by TheDon March 05, 2004
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48
by Jule March 22, 2004
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49
to be taken down relentlessly
E.g. u down, u facken down. (often used on computer games)
by Mojo April 07, 2004
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