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1.
To make out or hooking up.
see also do stuff and more
Dude, I'm going to do stuff with that broad later if she's drunk enough.
by king lenny October 16, 2005
 
2.
The act of doing many things at once while intoxicated
Desi dostuff during spring break.
by Desi "Spermy Luva" Delgado March 25, 2004