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pretty girl disease 

1. The condition of a physically appealing female with no other attractive features aside from appearance.
2. a. When an attractive young woman loses the ability to interact with others on a socially meaningful level, usually due to low self-esteem, a superiority complex, and excessive flattery at a young age.
b. The opposite of ugly duckling syndrome.
1. Wow, girl x is hot, but she only sits around and smokes.
2. a. Girl x probably does nothing because people who say they care about her only care about her looks.
b. It's too bad girl x became attractive so early in life; now she has serious issues, pretty girl disease, and is a camwhore.
pretty girl disease by Xkazy July 22, 2006
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dumb white girl disease 

White girls who pay bills, give money to, provide housing for, and offer sexual loyalty to guys of other races with no relationship commitment from them in exchange for attention and sex. May or may not end up being a babymomma, which is irrelevant. Dumb white disease (otherwise known as DWD) usually continues until the white girl runs out of money and/or becomes a victim of physical violence at which point she may have a moment of enlightenment; however, many relapse into DWD again and continue the cycle.
Why is Kristy letting him move in with her when he doesn't even have a job and 2 babymommas? Girl I told you she's got dumb white girl disease (DWD).

White Girl Disease 

A condition in which any part of the populous, excluding the white girl, starts to act and channel their inner white girl. Familiar symptoms include buying frappucinos from Starbucks and having a Tumblr account. Other symptoms may include constant bitching and or excessive phone usage.
Martha: Rick, I think Becky is coming down with White Girl Disease...

Rick: Get her to the hospital! This shit is deadly Martha!
White Girl Disease by Nugpon May 26, 2016

pretty girl disease 

Basically when a girl suddenly changes into more of a 'girlie girl'. She starts focusing on her overall appearance. Churchies tend to use this term for girls that walk away because they prefer to fit in with the popular kids.
Person1: What's with Ashley? She hasn't been to service in weeks.
Person2: Oh, she got the pretty girl disease.
Person1: I knew she kicked her look up a knotch.

beautiful girl disease 

when a girl is younger she is beautiful and therefore pampered, but once she is older and ugly she no longer gets that attention and therefore lives a very boring life, usually short and depressing
Brad: Wow, she used to be so pretty and successful, until she got fugly
Jim: Yeah, she's got a major case of beautiful girl disease

hot girl disease

"She's so Leah! She must have hot girl disease."

Hot girl disease

When you text a girl and she texts you with a ,” can I wear your hoodie.” And you just sit there going should I let her wear it. Then she hits you with a ,” can you do what I say.” Your heart is 50/50 because you don’t know if she is bein controlling or being nice. She passes this disease down from girl to girl and the only way to stop it is by getting a bf. If you see a girl with hot girl disease and if you ain’t her boyfriend your pants will be wet for reasons only guys know if
Hot girl disease by XDXDXDXD ROARRR December 31, 2018