A .22lr calibre firearm.
The silly muthufucku pulls out a deuce-deuce. Little did he know I had a loaded 12-gauge.
by nokianinja October 07, 2002
Although commonly misconceived as a .22 caliber gun, a deuce deuce is indeed a handgun. However, it is not .22 caliber. A deuce deuce is an Austrian made Glock pistol model number 22. The Glock 22 pistol fires .40S&W rounds, not .22 caliber.

Noun: Glock 22 Handgun

The deuce deuce was made famous by many rappers and musicians.
"And the deuce deuce in my bubblegoose"
-- Notorious B.I.G.

"About to get loose with the deuce deuce"
-- Ice Cube

"I got the deuce deuce in the trunk of my car, Oh yeah"
-- Sublime
by Hawk Diggity February 14, 2010
A 22 ounce bottle of (malt) liquor.
"Gimme a couple dollars so I can bring you back a deuce-deuce nigga!"
by Cecil Beals November 02, 2007
another term for 22-inch rims
white kid: Did you see that sick ass Expedizzle skirting on deuce-deuces?

black kid: Why the fuck do you even open your mouth?
by big body Benz June 07, 2006
two middle fingers or fuck you
*passing the police* deuce deuce
by ReubenQ June 18, 2011
22oz. of beer.
.22 caliber gun.
"I got the deuce-deuce in the trunk of my car, oh yeah" - Sublime

"Yo, dont forget my deuce-deuce!" - Me ;]
by fiercebanana July 10, 2008
nick name for the 22 Illini MTD bus route at Unniversity of Illinois in Urbana Champaign.
How can i get to the ARC?
Just hop on the deuce deuce
by Chief123456789 December 01, 2010
Your second poop of the day.
- How you feeling?

- Better now after my deuce deuce. I made a run for the boarder WAY too late last night.
by tyc303 July 28, 2010

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