Top Definition
word used to describe friends or anyone you don't know
what up cuzo
man cuzo i ain't seen you in a long time
by JD Smooth February 15, 2005
your guy your best friend an acautence
used in the ill mill(milwaukee) or midwest
whats good Cuzo what you been up to
by sicilian soilder November 05, 2006
A cousin instead, of saing cousin...and sound lame use cuz-o to sound cool.!!
Yo wats up this is my cuz-o, Alexus!
Yo I want you to meet my cuz-o.
by Jazmyn luvs Alexus 4-life January 16, 2008
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