Top Definition
(adj) A concatenation of the words confused and baffled. To be confuffled is to be visibly disoriented and perplexed.

"After a few moments of intense discussion, the teenaged girl flounced off and the boy watched her go, a confuffled expression on his face."
by Silkenvoice April 25, 2008
A feeling when you are confused
Christopher felt confuffled or confused when he didn't understand.
by Futurama Lover June 09, 2015

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