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mentally retarded; also considered to have a mental or physical disorder,
Tiffany is so challenged because she has a disorder in her armpit.
by Juleus Pdot January 31, 2007
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2

1. A person who creatively and successfully deals with all of life's challenges.

A synonym for fucked up.

Cousin Sam is challenged.
by ~a and ~d October 26, 2007
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