The couple Callie/Arizona from the fictional hit drama, Grey's Anatomy. The couple is currently the only lesbian couple on primetime television. The characters are portrayed as Sara Ramirez (Callie) and Jessica Capshaw (Arizona).
"Did you watchGrey's last night?"
"YES! Calzona broke up."
"It's okay though, they're MFEO.
slang; disparaging and offensive; a derogative term originated from western Massachusetts which implies a male homosexual who likes to order homoerotic food
Cory was creeping around on the phone for a very long time. It's possible he was talking to a flaming calzone for dinner.