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it means "nothing". zip, zilch, zero.
me: "i've got a pair of aces, what do you have?"
you: "i've got bupkiss (nothing, or a 5 of clubs and a deuce of diamonds, etc.)"
bupkiss by ert August 23, 2004
Related Words
I put a lot of hard work into this project, and all I got was bupkis.
bupkis by tradesman May 7, 2003
Nothing of value. From Yiddish 'bobkes;, meaning 'little beans'. See bupkis
"We got bubkes! We turn ourselves in now, they'll give us twenty years in the electric chair!" -- Dan Aykroyd as "Mother", in Sneakers (1992)
bubkes by Moshe Jacobson November 9, 2004
Literally, in Yiddish it means "beans". However, beans was a term used to describe goat droppings, as goat shit looks like beans.

So bupkis or bupkes is a common slang for, 'of no value". That is what the slang means. The reason for that is above. It does not literally mean "goat shit". It means "beans".
I worked my ass off on this project and got exactly bupkis for my troubles.
bupkis by linguistication January 1, 2016
Also spelled bubkes but still means the same thing. The word Bupkis means 'nothing, zero, having no value'. Also it is said by the television character Dr. Zoidberg on the show "Futurama" since he is a Jewish lobster and this word has a Jewish origin it all makes sense.
Zoidberg: "We've had president Bush for four years and all we got was Bupkis"
Bupkis by Jeremy K. October 27, 2004

Fist Bupkis 

An awkward unconsummated fist bump.

Person A goes in with a fist bump. Person B goes in with a handshake.
Both thinking they have done the wrong thing, and reverse their plan.
Now Person A goes in with a handshake, and Person B goes in with a fist bump.
At this point, both are feeling awkward and give up on the whole thing.
“Yeah, it was a bit awkward. When the interview started, the nerdy manager was trying a little too hard and went for the fist bump. Ended in fist bupkis, and it went downhill from there.”
Fist Bupkis by WordsbyW January 23, 2020