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3.
A girl who just by looking at her face has, will or wants to fuck primarily black males. Usually trashy looking as well. It is similar to being able to tell that someone has Down syndrome just by their face.
That girl obviously has brown syndrome.
by Dane cook July 03, 2013
 
1.
the extreme of being black or acting black
Man Sierra B, got brown syndrome
by xDarbyx April 04, 2010
 
2.
When a white person dresses, talks and acts like a black person.
Dude why is britney talking and acting like that?

Dude thats not cool, she has Brown Syndrome
by Damienod January 10, 2014