To have a problem with someone. It is usually referring to a characteristic you don't like about them.
The only bone I have with Mike is that he talks shit about some people that don't deserve it.
by Janis March 16, 2005
Also...

1) Dice. Note that this sense is never used singularly - you never roll "a bone", you roll "the bones". Origin unclear - but I suspect it has something to do with certain voodoo in which a practicer would cast bones for fortune telling.

2) Monetary units, usually US dollars. Used for high numbers generally. Origin again unclear here, but possibly alludes to an arm and a leg.
2) Dude, that designer shirt is gonna cost you fifty bones.
by ke6isf January 31, 2005
bone! mans penis. or something thats in everybody! give the dog a bone!
old mother hubbard went to the cupboard,
to give rover a bone.
when old mother went to bend over,
rover gave her a bone of her own!

gurl i love every bone in your body,
especially mine!
by FREAK KORN March 31, 2004
1.) An erect penis
2.) sexual intercourse
3.) white structural interior portion of a mammal.
Fishing wit my bone, fishin' wit' my bone... at the lake I sit on my throne, get to the lake, pull out my line tie that shit to my bone cause it feels fine
if a fucking fish hits it should be told my bone stops bobbing like morse code, boop boop boo boop boo boop...
by Bitchfuckers September 24, 2003
Acronym used by Bone Thugs~N~Harmony when they were formerly called B.O.N.E. Enterpri$e. Has various meanings.
Brewed Out Niggas Everyday, Bustin' On Niggas Everyday.
by rxl March 28, 2003
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