Top Definition
1. n. the general stank and moist nastiness that develop in one's crotch as a result of sweat and rapid movement of the legs.

2. n. the effect of sweaty, humid testicles and the general torquing motion of walking on ones boxers, briefs and pants.

3. v. to develop ball rot and/or specifically apply it to a fabric.
1. "I'm so sweaty from soccer practice. I've got a serious case of ball rot."

2. "Chris, dude. I've got holes in my boxers from ball rot."

3. "I had to throw away some boxers because they were seriously ball rotted."
by A. J. February 20, 2007
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